Renal dopamine and salt sensitivity of blood pressure in IgA nephropathy

Background: Patients with chronic glomerulonephritis exhibit salt-sensitive ( SS) hypertension. In the early stage, however, the exact characteristics are still unclear. A decrease in renal dopamine production under basal conditions or after a sodium load has been reported in a subset of patients with SS primary hypertension. Aims: The present study examined 17 untreated IgA-N patients with near-normal renal function, to determine whether salt sensitivity appears before hypertension and wheth...

Arterial distensibility in subjects with white-coat hypertension with and without diabetes or dyslipidaemia: comparison with normotensives and sustained hypertensives

Objective To determine whether diabetes, smoking and dyslipidaemia were associated with greater than normal stiffness of aortic walls in subjects with white-coat hypertension. Methods Arterial distensibility was assessed by automatic measurement of carotid-femoral PWV in 35 healthy normotensives, 46 white-coat hypertensives (WCH, clinic blood pressures > 140/90 mmHg, daytime blood pressures < 130/85 mmHg) and 81 ambulatory hypertensives (clinic blood pressures > 140/90 mmHg, daytime blood pre...

Visualização e quantificação da estenose carotídea usando imagens de ultrassonografia

Intestinal permeability to glucose after experimental traumatic brain injury: Effect of gadopentetate dimeglumine administration

Traumatic injuries are the leading cause of mortality in individuals aged 1-44 years, and brain injury significantly contributes to the outcome in nearly one half of all deaths from trauma. At the intestinal level, traumatic brain injury (TBI) induces profound effects, including gastrointestinal mucosa ischaemia and motility dysfunction. However, nothing is known concerning the effect of TBI on the intestinal absorption of glucose. Hence, the aim of this study was to investigate the effect of...