Three-Dimensional Triple Negative Breast Cancer Models: A Platform for Radiobiology Studies
Breast cancer (BC) is the leading cause of cancer related death and diagnose in women worldwide. (1) Due to its heterogeneous nature, BC is divided into subtypes depending on the expression of estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2). Based on these markers, four major subtypes of BC were designated: Luminal A like, Luminal B like, HER2 positive and Basal type (ER-, PR-, HER2-) also known as Triple-negative breast cancer (TNBC).
T...