Please use this identifier to cite or link to this item:
Author(s): Joana Matos
Nuno Vale
Margaret S Collins
Jiri Gut
Philip J Rosenthal
Melanie T Cushion
Rui Moreira
Paula Gomes
Title: PRIMACENES: novel non-cytotoxic primaquine-ferrocene conjugates with anti-Pneumocystis carinii activity
Issue Date: 2010
Abstract: Primacenes, novel ferrocene-primaquine conjugates, were synthesized and screened for their antimalarial and anti-pneumocystis activity. Primacenes obtained by coupling primaquine amino acid derivatives to ferrocenoic acid were significantly active against Pneumocystis carinii and devoid of cytotoxicity, thus being more selective than the parent drug.
Subject: Química
Chemical sciences
Scientific areas: Ciências exactas e naturais::Química
Natural sciences::Chemical sciences
Document Type: Artigo em Revista Científica Internacional
Rights: openAccess
Appears in Collections:FCUP - Artigo em Revista Científica Internacional

Files in This Item:
File Description SizeFormat 
89180.pdf128.06 kBAdobe PDFThumbnail

This item is licensed under a Creative Commons License Creative Commons