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https://hdl.handle.net/10216/82046| Author(s): | Mary K S Batista Marcal Gallemi Alberto Adeva Carlos A R Gomes Paula Gomes |
| Title: | Facile Regioselective Synthesis of a Novel Chitosan-Pexiganan Conjugate with Potential Interest for the Treatment of Infected Skin Lesions |
| Issue Date: | 2009 |
| Abstract: | A pexiganan-chitosan conjugate was designed to combine the exceptional bioadhesion and tissue-regenerating abilities of chitosan with the excellent antibiotic properties of pexiganan. We herein report our first results on the successful synthesis, including Fourier transform infrared (FT-IR) and amino acid analysis of such conjugate, which was prepared by regioselective covalent attachment of a Cys-containing pexiganan analog to the chitosan's amino groups. Further results from ongoing research will be reported. |
| Subject: | Química Chemical sciences |
| Scientific areas: | Ciências exactas e naturais::Química Natural sciences::Chemical sciences |
| DOI: | 10.1080/00397910802517855 |
| URI: | https://hdl.handle.net/10216/82046 |
| Document Type: | Artigo em Revista Científica Internacional |
| Rights: | openAccess |
| License: | https://creativecommons.org/licenses/by-nc/4.0/ |
| Appears in Collections: | FCUP - Artigo em Revista Científica Internacional |
This item is licensed under a Creative Commons License
