Impacto da sucralose na resposta pós-prandial glicémica e insulinémica e na secreção de GLP-1 em adultos: revisão sistemática e meta-análise
Background and Objectives: The metabolic neutrality of non-nutritive sweeteners (NNS) remains inconsistent. This systematic review and meta-analysis evaluated the acute effects of sucralose, alone or with carbohydrates, on postprandial glycemic, insulinemic, and glucagon-like peptide-1 (GLP-1) responses in adults.
Methods: Following PRISMA guidelines, the search was conducted across PubMed and Web of Science up to November 1, 2025, for randomized controlled trials (RCTs) assessing glycemic an...