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https://hdl.handle.net/10216/67153
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DC Field | Value | Language |
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dc.creator | Hernani Goncalves | |
dc.creator | Tiago Henriques Coelho | |
dc.creator | Ana Paula Rocha | |
dc.creator | Andre P Lourenco | |
dc.creator | Adelino Leite Moreira | |
dc.creator | Joao Bernardes | |
dc.date.accessioned | 2022-09-07T12:57:09Z | - |
dc.date.available | 2022-09-07T12:57:09Z | - |
dc.date.issued | 2013 | |
dc.identifier.issn | 1350-4533 | |
dc.identifier.other | sigarra:81587 | |
dc.identifier.uri | https://hdl.handle.net/10216/67153 | - |
dc.description.abstract | Acute life-threatening situations are particularly critical when superimposed on chronic diseases. The objective of this study was the assessment of heart rate (HR) dynamics during episodes of acute anoxia superimposed on a rat model of chronic pulmonary hypertension. In 10 adult Wistar rats, five weeks after pulmonary hypertension induction with Monocrotaline, we analysed eight 1-min HR segments, during episodes of baseline, mechanical ventilation and acute anoxia, using linear indices, approximate entropy (ApEn), sample entropy (SampEn) and multiscale entropy (MSE). The transition from baseline or mechanical ventilation to early anoxia was identified through almost all indices, but SampEn(2,0.6) was the index that better identified all the transitions. MSE presented limited performance, possibly due to the non-stationary nature and short duration of the acute anoxia episodes. A systematic evaluation of all computed HR indices may help to identify which indices or combination of indices more adequately discriminates and monitors critical acute events superimposed on chronic clinical conditions. | |
dc.language.iso | eng | |
dc.rights | openAccess | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc/4.0/ | |
dc.subject | Biotecnologia ambiental | |
dc.subject | Environmental biotechnology | |
dc.title | Comparison of different methods of heart rate entropy analysis during acute anoxia superimposed on a chronic rat model of pulmonary hypertension | |
dc.type | Artigo em Revista Científica Internacional | |
dc.contributor.uporto | Faculdade de Ciências | |
dc.contributor.uporto | Faculdade de Medicina | |
dc.identifier.doi | 10.1016/j.medengphy.2012.06.020 | |
dc.identifier.authenticus | P-005-163 | |
dc.subject.fos | Ciências da engenharia e tecnologias::Biotecnologia ambiental | |
dc.subject.fos | Engineering and technology::Environmental biotechnology | |
Appears in Collections: | FCUP - Artigo em Revista Científica Internacional FMUP - Artigo em Revista Científica Internacional |
This item is licensed under a Creative Commons License