Please use this identifier to cite or link to this item: https://hdl.handle.net/10216/116074
Author(s): Fernandes, RM
Silva, H
Ricardo Jorge Dinis Oliveira
Almeida, C
Azevedo, NF
Vieira, MJ
Title: Morphological transition of Helicobacter pylori adapted to water
Issue Date: 2017
Abstract: Aim: This study aims to investigate the morphological transition of Helicobacter pylori during adaptation to water. Materials & methods: Different strains were adapted to water. Changes regarding cultivability and cellular morphology were recorded. Expression of 11 genes involved in H. pylori morphological changes was evaluated by real-time PCR. Results: H. pylori presented increased cultivability in water after adaptation. The permanent loss of the spiral shape was observed, but no transition into coccoid form has occurred. Expression levels of genes involved in peptidoglycan assembly of H. pylori 26695 have shown significant changes between adapted and nonadapted strains. Conclusion: Adaption to water favors the culturable phenotype and the morphological transition to the rod shape, into a process that implicates the peptidoglycan turnover.
URI: https://repositorio-aberto.up.pt/handle/10216/116074
Document Type: Artigo em Revista Científica Internacional
Rights: restrictedAccess
Appears in Collections:FMUP - Artigo em Revista Científica Internacional
ICBAS - Artigo em Revista Científica Internacional

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