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https://hdl.handle.net/10216/101737Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.creator | Rui Adao | |
| dc.creator | Diana Santos Ribeiro | |
| dc.creator | Miriam T Rademaker | |
| dc.creator | Adelino F Leite Moreira | |
| dc.creator | Carmen Bras Silva | |
| dc.date.accessioned | 2022-09-08T09:15:19Z | - |
| dc.date.available | 2022-09-08T09:15:19Z | - |
| dc.date.issued | 2015 | |
| dc.identifier.issn | 1359-6446 | |
| dc.identifier.other | sigarra:107267 | |
| dc.identifier.uri | https://hdl.handle.net/10216/101737 | - |
| dc.description.abstract | Urocortin (Ucn)-2 - corticotropin-releasing hormone receptor 2 signaling has favorable effects in the cardiovascular system, including coronary vasodilatation, with increased coronary blood flow and conductance and augmented cardiac contractility and output, as well as protection against ischemia/reperfusion injury. Indeed, several animal studies have confirmed the salutary therapeutic effects of Ucn-2 in chronic heart failure, with improvements in cardiac performance and animal survival. In addition, recent clinical trials have demonstrated the benefits of Ucn-2 in patients with stable chronic heart failure on optimal medical therapy. | |
| dc.language.iso | eng | |
| dc.rights | restrictedAccess | |
| dc.subject | Medicina básica | |
| dc.subject | Basic medicine | |
| dc.title | Urocortin 2 in cardiovascular health and disease | |
| dc.type | Artigo em Revista Científica Internacional | |
| dc.contributor.uporto | Faculdade de Ciências da Nutrição e Alimentação | |
| dc.identifier.doi | 10.1016/j.drudis.2015.02.012 | |
| dc.identifier.authenticus | P-00G-J1Q | |
| dc.subject.fos | Ciências médicas e da saúde::Medicina básica | |
| dc.subject.fos | Medical and Health sciences::Basic medicine | |
| Appears in Collections: | FCNAUP - Artigo em Revista Científica Internacional | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 107267.pdf Restricted Access | 1.56 MB | Adobe PDF | View/Open |
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