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https://hdl.handle.net/10216/101737| Author(s): | Rui Adao Diana Santos Ribeiro Miriam T Rademaker Adelino F Leite Moreira Carmen Bras Silva |
| Title: | Urocortin 2 in cardiovascular health and disease |
| Issue Date: | 2015 |
| Abstract: | Urocortin (Ucn)-2 - corticotropin-releasing hormone receptor 2 signaling has favorable effects in the cardiovascular system, including coronary vasodilatation, with increased coronary blood flow and conductance and augmented cardiac contractility and output, as well as protection against ischemia/reperfusion injury. Indeed, several animal studies have confirmed the salutary therapeutic effects of Ucn-2 in chronic heart failure, with improvements in cardiac performance and animal survival. In addition, recent clinical trials have demonstrated the benefits of Ucn-2 in patients with stable chronic heart failure on optimal medical therapy. |
| Subject: | Medicina básica Basic medicine |
| Scientific areas: | Ciências médicas e da saúde::Medicina básica Medical and Health sciences::Basic medicine |
| URI: | https://hdl.handle.net/10216/101737 |
| Document Type: | Artigo em Revista Científica Internacional |
| Rights: | restrictedAccess |
| Appears in Collections: | FCNAUP - Artigo em Revista Científica Internacional |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 107267.pdf Restricted Access | 1.56 MB | Adobe PDF | Request a copy from the Author(s) |
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