Please use this identifier to cite or link to this item:
https://hdl.handle.net/10216/95481
Author(s): | Santos, NC Costa, P Ruano, D MacEdo, A Soares, MJ Valente, J Pereira, AT Azevedo, MH Palha, JA |
Title: | Revisiting thyroid hormones in schizophrenia |
Issue Date: | 2012 |
Abstract: | Thyroid hormones are crucial during development and in the adult brain. Of interest, fluctuations in the levels of thyroid hormones at various times during development and throughout life can impact on psychiatric disease manifestation and response to treatment. Here we review research on thyroid function assessment in schizophrenia, relating interrelations between the pituitary-thyroid axis and major neurosignaling systems involved in schizophrenia's pathophysiology. These include the serotonergic, dopaminergic, glutamatergic, and GABAergic networks, as well as myelination and inflammatory processes. The available evidence supports that thyroid hormones deregulation is a common feature in schizophrenia and that the implications of thyroid hormones homeostasis in the fine-tuning of crucial brain networks warrants further research. © 2012 Nadine Correia Santos et al. |
Subject: | Psicologia Psychology |
Scientific areas: | Ciências sociais::Psicologia Social sciences::Psychology |
URI: | https://repositorio-aberto.up.pt/handle/10216/95481 |
Document Type: | Artigo em Revista Científica Internacional |
Rights: | restrictedAccess |
Appears in Collections: | FPCEUP - Artigo em Revista Científica Internacional |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
88158.pdf Restricted Access | 1.27 MB | Adobe PDF | Request a copy from the Author(s) |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.