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https://hdl.handle.net/10216/91713| Author(s): | Pedro Mendes Ferreira Gilles W De Keulenaer Adelino F Leite Moreira Carmen Bras Silva |
| Title: | Therapeutic potential of neuregulin-1 in cardiovascular disease |
| Issue Date: | 2013 |
| Abstract: | Neuregulin-1 (NRG-1)/ErbB signaling has an indispensable role in cardiac development and in the maintenance of the structural and functional integrity of the human adult heart in health and disease. Several animal studies have now demonstrated the therapeutic effects of NRG-1 during acute cardiac injury and during chronic heart failure, with improvements in cardiac performance and animal survival. Phase I and II clinical trials for chronic heart failure in humans are now in progress. |
| Subject: | Ciências da Saúde, Medicina básica Health sciences, Basic medicine |
| Scientific areas: | Ciências médicas e da saúde::Medicina básica Medical and Health sciences::Basic medicine |
| DOI: | 10.1016/j.drudis.2013.01.010 |
| URI: | https://hdl.handle.net/10216/91713 |
| Document Type: | Outra Publicação em Revista Científica Internacional |
| Rights: | restrictedAccess |
| Appears in Collections: | FMUP - Outra Publicação em Revista Científica Internacional |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 47937.pdf Restricted Access | 443.59 kB | Adobe PDF | View/Open |
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