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Author(s): Pedro Mendes Ferreira
Gilles W De Keulenaer
Adelino F Leite Moreira
Carmen Bras Silva
Title: Therapeutic potential of neuregulin-1 in cardiovascular disease
Issue Date: 2013
Abstract: Neuregulin-1 (NRG-1)/ErbB signaling has an indispensable role in cardiac development and in the maintenance of the structural and functional integrity of the human adult heart in health and disease. Several animal studies have now demonstrated the therapeutic effects of NRG-1 during acute cardiac injury and during chronic heart failure, with improvements in cardiac performance and animal survival. Phase I and II clinical trials for chronic heart failure in humans are now in progress.
Subject: Ciências da Saúde, Medicina básica
Health sciences, Basic medicine
Scientific areas: Ciências médicas e da saúde::Medicina básica
Medical and Health sciences::Basic medicine
Document Type: Outra Publicação em Revista Científica Internacional
Rights: restrictedAccess
Appears in Collections:FMUP - Outra Publicação em Revista Científica Internacional

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