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Author(s): Ricardo Jorge Dinis Oliveira
Title: Metabolomics of cocaine: implications in toxicity
Issue Date: 2015
Abstract: Cocaine is the most commonly used illicit drug among those seeking care in Emergency Departments or drug detoxification centers. Cocaine, chemically known as benzoylmethylecgonine, is a naturally occurring substance found in the leaves of the Erythroxylum coca plant. The pharmacokinetics of cocaine is dependent on multiple factors, such as physical/chemical form, route of administration, genetics and concurrent consumption of alcohol. This review aims to discuss metabolomics of cocaine, namely by presenting all known metabolites of cocaine and their roles in the cocaine-mediated toxic effects.
Document Type: Outra Publicação em Revista Científica Internacional
Rights: restrictedAccess
Appears in Collections:FMUP - Outra Publicação em Revista Científica Internacional

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