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https://hdl.handle.net/10216/82077
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DC Field | Value | Language |
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dc.creator | Eduardo F Marques | |
dc.creator | Rodrigo O Brito | |
dc.creator | Sandra G Silva | |
dc.creator | Enrique E Rodriguez Borges | |
dc.creator | Maria Luisa do Vale | |
dc.creator | Paula Gomes | |
dc.creator | Maria J Araujo | |
dc.creator | Olle Soderman | |
dc.date.accessioned | 2022-09-07T13:34:44Z | - |
dc.date.available | 2022-09-07T13:34:44Z | - |
dc.date.issued | 2008 | |
dc.identifier.issn | 0743-7463 | |
dc.identifier.other | sigarra:89155 | |
dc.identifier.uri | https://hdl.handle.net/10216/82077 | - |
dc.description.abstract | The use of amino acids for the synthesis of novel surfactants with vesicle-forming properties potentially enhances the biocompatibility levels needed for a viable alternative to conventional lipid vesicles. In this work, the formation and characterization of catanionic vesicles by newly synthesized lysine- and serine-derived surfactants have been investigated by means of phase behavior mapping and PFG-NMR diffusometry and cryo-TEM methods. The lysine-derived surfactants are double-chained anionic molecules bearing a pseudogemini configuration, whereas the serine-derived amphiphile is cationic and single-chained. Vesicles form in the cationic-rich side for narrow mixing ratios of the two amphiphiles. Two pairs of systems were studied: one symmetric with equal chain lengths, 2C(12)/C(12), and the other highly asymmetric with 2C(8)/C(16) chains, where the serine-based surfactant has the longest chain. Different mechanisms of the vesicle-to-micelle transition were found, depending on symmetry: the 2C12/C12 system entails limited micellar growth and intermediate phase separation, whereas the 2C(8)/C(16) system shows a continuous transition involving large wormlike micelles. The results are interpreted on the basis of currently available models for the micelle-vesicle transitions and the stabilization of catanionic vesicles (energy of curvature vs mixing entropy). | |
dc.language.iso | eng | |
dc.rights | openAccess | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc/4.0/ | |
dc.subject | Engenharia dos materiais | |
dc.subject | Materials engineering | |
dc.title | Spontaneous vesicle formation in catanionic mixtures of amino acid-based surfactants: Chain length symmetry effects | |
dc.type | Artigo em Revista Científica Internacional | |
dc.contributor.uporto | Faculdade de Ciências | |
dc.identifier.doi | 10.1021/la801518h | |
dc.identifier.authenticus | P-003-VJF | |
dc.subject.fos | Ciências da engenharia e tecnologias::Engenharia dos materiais | |
dc.subject.fos | Engineering and technology::Materials engineering | |
Appears in Collections: | FCUP - Artigo em Revista Científica Internacional |
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