Please use this identifier to cite or link to this item: https://hdl.handle.net/10216/81047
Author(s): P. C. Sousa
J. Carneiro
R. Vaz
A. Cerejo
Fernando Tavares de Pinho
Manuel Alves
Mónica Oliveira
Title: Shear viscosity and nonlinear behavior of whole blood under large amplitude oscillatory shear
Issue Date: 2013
Abstract: We investigated experimentally the rheological behavior of whole human blood subjected to large amplitude oscillatoryshear under strain control to assess its nonlinear viscoelastic response. In these rheological tests, the shear stress responsepresented higher harmonic contributions, revealing the nonlinear behavior of human blood that is associated with changes in itsinternal microstructure. For the rheological conditions investigated, intra-cycle strain-stiffening and intra-cycle shear-thinningbehavior of the human blood samples were observed and quantified based on the LissajousBowditch plots. The results demonstratedthat the dissipative nature of whole blood is more intense than its elastic component. We also assessed the effect ofadding EDTA anticoagulant on the shear viscosity of whole blood subjected to steady shear flow. We found that the use ofanticoagulant in appropriate concentrations did not influence the shear viscosity and that blood samples without anticoagulantpreserved their rheological characteristics approximately for up to 8 minutes before coagulation became significant.
Subject: Ciências da engenharia e tecnologias
Engineering and technology
Scientific areas: Ciências da engenharia e tecnologias
Engineering and technology
URI: https://repositorio-aberto.up.pt/handle/10216/81047
Related Information: info:eu-repo/grantAgreement/FCT - Fundação para a Ciência e Tecnologia/Projectos de I&DT em Todos os Domínios Científicos/PTDC/EME-MFE/099109/2008/ANEURYSM - Estudo Hemodinâmico em Aneurismas Cerebrais/ANEURYSM
info:eu-repo/grantAgreement/FCT - Fundação para a Ciência e Tecnologia/Projectos de I&DT em Todos os Domínios Científicos/PTDC/SAU-BEB/105650/2008/CSD-Chip - Desenvolvimento de um biochip para a separação e deformação de células sanguíneas/CSD-Chip
info:eu-repo/grantAgreement/FCT - Fundação para a Ciência e Tecnologia/Projectos de I&DT em Todos os Domínios Científicos/PTDC/EQU-FTT/118716/2010/Design de um "reómetro-num-chip" para o desenvolvimento de fluidos análogos ao sangue/RheoChip
Document Type: Artigo em Revista Científica Internacional
Rights: openAccess
License: https://creativecommons.org/licenses/by-nc/4.0/
Appears in Collections:FEUP - Artigo em Revista Científica Internacional
FMUP - Artigo em Revista Científica Internacional

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