Please use this identifier to cite or link to this item: https://hdl.handle.net/10216/72875
Full metadata record
DC FieldValueLanguage
dc.creatorGomes, AC
dc.creatorFalcao Pires, I
dc.creatorPires, AL
dc.creatorBras Silva, C
dc.creatorLeite Moreira, AF
dc.date.accessioned2022-09-08T10:48:11Z-
dc.date.available2022-09-08T10:48:11Z-
dc.date.issued2013
dc.identifier.issn1382-4147
dc.identifier.othersigarra:47826
dc.identifier.urihttps://hdl.handle.net/10216/72875-
dc.description.abstractHeart failure (HF) is one of the major health and economic burdens worldwide, and its prevalence is continuously increasing. The study of HF requires reliable animal models to study the chronic changes and pharmacologic interventions in myocardial structure and function and to follow its progression toward HF. Indeed, during the past 40 years, basic and translational scientists have used small animal models to understand the pathophysiology of HF and find more efficient ways of preventing and managing patients suffering from congestive HF (CHF). Each species and each animal model has advantages and disadvantages, and the choice of one model over another should take them into account for a good experimental design. The aim of this review is to describe and highlight the advantages and drawbacks of some commonly used HF rodents models, including both non-genetically and genetically engineered models, with a specific subchapter concerning diastolic HF models.
dc.language.isoeng
dc.rightsopenAccess
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/
dc.subjectCiências da Saúde, Medicina clínica
dc.subjectHealth sciences, Clinical medicine
dc.titleRodent models of heart failure: an updated review
dc.typeOutra Publicação em Revista Científica Internacional
dc.contributor.uportoFaculdade de Medicina
dc.identifier.doi10.1007/s10741-012-9305-3
dc.identifier.authenticusP-002-02V
dc.subject.fosCiências médicas e da saúde::Medicina clínica
dc.subject.fosMedical and Health sciences::Clinical medicine
Appears in Collections:FMUP - Outra Publicação em Revista Científica Internacional

Files in This Item:
File Description SizeFormat 
47826.pdfEpub 25 March 2012558.98 kBAdobe PDFThumbnail
View/Open
47826.1.pdfVersão publicada em 2013541.21 kBAdobe PDFThumbnail
View/Open


This item is licensed under a Creative Commons License Creative Commons