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Author(s): Lima, E
Rolanda, C
Osório, L
Pêgo, M
Silva, D
Henriques-Coelho, T
Carvalho, JL
Bergström, M
Park, PO
Mosse, CA
Swain, P
Contributor(s): Correia-Pinto, J
Title: Endoscopic Closure of Transmural Bladder Wall Perforations
Issue Date: 2009
Abstract: endoscopic surgery (NOTES) but would be enhanced by a reliable method of closing the vesicotomy.OBJECTIVE:To assess the feasibility and safety of an endoscopic closure method for vesical perforations using a flexible, small-diameter endoscopic suturing kit in a survival porcine model.DESIGN, SETTING, AND PARTICIPANTS:This pilot study was performed at the University of Minho, Braga, Portugal, using six anesthetized female pigs.INTERVENTIONS:Closure of a full-thickness longitudinal incision in the bladder dome (up to 10 mm in four animals and up to 20 mm in two animals) with the endoscopic suturing kit using one to three absorbable stitches.MEASUREMENTS:The acute quality of sealing was immediately tested by distending the bladder with methylene-blue dye under laparoscopic control (in two animals). Without a bladder catheter, the animals were monitored daily for 2 wk, and a necropsy examination was performed to check for the signs of peritonitis, wound dehiscence, and quality of healing.RESULTS AND LIMITATIONS:Endoscopic closure of bladder perforation was carried out easily and quickly in all animals. The laparoscopic view revealed no acute leak of methylene-blue dye after distension of the bladder. After recovery from anaesthesia, the pigs began to void normally, and no adverse event occurred. Postmortem examination revealed complete healing of vesical incision with no signs of infection or adhesions in the peritoneal cavity. No limitations have yet been studied clinically.CONCLUSIONS:This study demonstrates the feasibility and the safety of endoscopic closure of vesical perforations with an endoscopic suturing kit in a survival porcine model. This study provides support for further studies using endoscopic closure of the bladder which may lead to a new era in management of bladder rupture and adoption of the transvesical port in NOTES procedures.
Subject: Ciências médicas e da saúde
Medical and Health sciences
Scientific areas: Ciências médicas e da saúde
Medical and Health sciences
Document Type: Artigo em Revista Científica Internacional
Rights: openAccess
Appears in Collections:FMUP - Artigo em Revista Científica Internacional

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