Avaliação dos fatores de risco asssociados ao abandono do Tratamento de Tuberculose antes e durante a pandemia de Covid -19 no Município de São Paulo, Brasil.

Abstract

The Covid-19 pandemic has affected the management of patients with Tuberculosis (TB) due to health services being practically directed to Covid-19 cases. It is estimated that interruption of TB programs during the lockdown period could lead to an additional 6.3 million new cases and 1.4 million deaths globally. Several factors associated with non-adherence and abandonment of TB treatment have been reported in the literature, including factors related to the patient, the disease, socioeconomic conditions and health services. At the moment, studies are needed to assess whether the pandemic has affected the continuity of TB treatments. The present study intends to evaluate the risk factors associated with abandonment of TB treatment before and during the pandemic in the city of São Paulo, Brazil, through a cross-sectional study based on the analysis of the TB-Web database (São Paulo State Department of Health TB Notification and Monitoring System) of notified TB cases of residents in the city of São Paulo from March 2019 to February 2021. The project will be submitted to the Plataforma Brasil (national base and unified records of research involving human beings for the entire system of the Ethics and Research Committee - CEP/ National Research Ethics Committee - Conep) and after approval by the Ethics Committee, the data will be analyzed. Statistical analysis includes descriptive analysis of categorical variables and continuous variables. In the inferential analysis, the significance level will be set at 0.05 and the association between abandonment treatment and the various risk factors will be evaluated using logistic regression models.