Fatores de risco associados a depressão no cancro da mama: uma revisão sistemática

Abstract

Introduction: Breast cancer is the most frequent malignant neoplasm in women worldwide, and depression is one of the most frequent psychiatric symptoms in these patients. The aim of this systematic review was to identify the risk factors associated with depression in patients with breast cancer. Methods: An article search was conducted in two databases to identify articles that studied the risk factors associated with depression in patients with breast cancer. The following query was used: ((breast cancer [MeSH Terms]) AND (risk factors [MeSH Terms])) AND (major depressive disorder [MeSH Terms]). A summary of the characteristics of the included studies, the prevalence of depression, the studied risk factors and the risk factors that were associated with depression in patients with breast cancer were summarized. Results: Eleven studies were included, all in women. The prevalence of depression in most studies ranged from 15-50%, but three studies had lower prevalence. The risk factors associated with depression were identified: adjuvant treatments for breast cancer, sociodemographic characteristics, clinical characteristics of the tumor, social and family support, insomnia, pain, fatigue, psychiatric precedents, daily living habits, passive coping style, childhood adversities, distress and recent diagnosis of breast cancer. Conclusion: In this systematic review, depression was a very common pathology in women with breast cancer, so the detection of women at risk proved to be very important for a good clinical practice, namely in its prevention and early diagnosis.