Neurosurgical anatomy of the insular cortex

Abstract

OBJECTIVE: The purpose of this study was to clarify the morphology of the insular cortex focusing not only on the shape of the insula, but also on sulcal and gyral organization. PATIENTS AND METHODS: Sixty formalin-fixed adult brain hemispheres had their insula exposed and photographed. The dimensions of each gyrus and sulcus were measured using an image analysis software. The morphometric data obtained was statistically analysed. RESULTS: The insular cortex shape alternates between triangular and trapezoid, being the triangular shape the most common (75%). The angle between the posterior and inferior peri-insular sulcus in the trapezoid insulae had a mean range of 131.17 (SD = 12.277). A minimum of 3 and a maximum of 6 insular gyri were observed, being 5 the most common total number of gyri observed. The accessory gyrus was present in 66% of the insulae and well-developed in 38% of the cases. A statistical association between the number of gyri in the posterior lobe and the presence of a novel gyrus or a more developed accessory gyrus in the anterior lobe was found (P = 0.006). The posterior short gyrus was the longest of the short gyri (P < 0.001), followed by the anterior short gyrus (P < 0.001). The anterior long gyrus was the largest of the long gyri (P = 0.003). The contribution of each of the short gyri to the formation of the insular apex was inconstant. The most common observed apex arrangement was the combination of the anterior and of the middle short gyri. CONCLUSIONS: This study makes a strong contribution to the understanding of the insular cortex anatomy, allowing neurosurgeons to be more capable to decide the best approach to this cortical area.