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Author(s): K. Slezakova
M. Oliveira
A. Fernandes
J. A. Vaz
C. Delerue Matos
J. P. Teixeira
M. C. Pereira
S. Morais
Title: Occurrence of polycyclic aromatic hydrocarbon metabolites in urine of Portuguese firefighters
Issue Date: 2015
Abstract: The present work estimates occupational exposure of healthy and non-smoking Portuguesefirefighters to polycyclic aromatic hydrocarbons (PAHs) through the analysis of four urinarymetabolites (OH-PAHs): 1-hydroxyacenaphthene, 1-hydroxynaphthalene, 1-hydroxypyrene(PAH biomarker of exposure), and 3-hydroxybenzo[a]pyrene (PAH biomarker ofcarcinogenicity). Firemen from several Portuguese corporations were asked to provide urinesamples during the winter period (without exposition to fires; pre-fire season) and during thesummer season of 2014 after fires fighting. The selected OH-PAHs were extracted from urinesamples by solid-phase extraction and analyzed by high-performance liquid chromatographywith fluorescence detection. Normalization of the urinary PAH-metabolite levels was achievedby analyzing the creatinine concentrations. 1-hydroxynaphthalene and 1-hydroxyacenaphthenewere the most abundant metabolites, followed by 1-hydroxypyrene. The metabolite 3-hydroxybenzo[a]pyrene was not detected. Total OH-PAHs ranged from 0.02 to 4.01 μmol/molcreatinine and between 0.55 to 8.39 μmol/mol creatinine, respectively, for non exposed andexposed firefighters. In general, the detected concentratio
Subject: Ciências do ambiente, Ciências da saúde
Environmental science, Health sciences
Scientific areas: Ciências médicas e da saúde::Ciências da saúde
Medical and Health sciences::Health sciences
Source: Proceedings of the 14th International Conference on Environmental Science and Technology (CEST2015)
Related Information: info:eu-repo/grantAgreement/FCT - Fundação para a Ciência e Tecnologia/Projetos Estratégicos/PEst-C/EQB/UI0511/2013/PROJECTO ESTRATÉGICO - UI 511 - 2013-2014/UI0511
Document Type: Artigo em Livro de Atas de Conferência Internacional
Rights: restrictedAccess
Appears in Collections:FEUP - Artigo em Livro de Atas de Conferência Internacional

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