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dc.creatorK. Slezakova
dc.creatorM. Oliveira
dc.creatorA. Fernandes
dc.creatorJ. A. Vaz
dc.creatorC. Delerue Matos
dc.creatorJ. P. Teixeira
dc.creatorM. C. Pereira
dc.creatorS. Morais
dc.description.abstractThe present work estimates occupational exposure of healthy and non-smoking Portuguesefirefighters to polycyclic aromatic hydrocarbons (PAHs) through the analysis of four urinarymetabolites (OH-PAHs): 1-hydroxyacenaphthene, 1-hydroxynaphthalene, 1-hydroxypyrene(PAH biomarker of exposure), and 3-hydroxybenzo[a]pyrene (PAH biomarker ofcarcinogenicity). Firemen from several Portuguese corporations were asked to provide urinesamples during the winter period (without exposition to fires; pre-fire season) and during thesummer season of 2014 after fires fighting. The selected OH-PAHs were extracted from urinesamples by solid-phase extraction and analyzed by high-performance liquid chromatographywith fluorescence detection. Normalization of the urinary PAH-metabolite levels was achievedby analyzing the creatinine concentrations. 1-hydroxynaphthalene and 1-hydroxyacenaphthenewere the most abundant metabolites, followed by 1-hydroxypyrene. The metabolite 3-hydroxybenzo[a]pyrene was not detected. Total OH-PAHs ranged from 0.02 to 4.01 μmol/molcreatinine and between 0.55 to 8.39 μmol/mol creatinine, respectively, for non exposed andexposed firefighters. In general, the detected concentratio
dc.relationinfo:eu-repo/grantAgreement/FCT - Fundação para a Ciência e Tecnologia/Projetos Estratégicos/PEst-C/EQB/UI0511/2013/PROJECTO ESTRATÉGICO - UI 511 - 2013-2014/UI0511
dc.relation.ispartofProceedings of the 14th International Conference on Environmental Science and Technology (CEST2015)
dc.subjectCiências do ambiente, Ciências da saúde
dc.subjectEnvironmental science, Health sciences
dc.titleOccurrence of polycyclic aromatic hydrocarbon metabolites in urine of Portuguese firefighters
dc.typeArtigo em Livro de Atas de Conferência Internacional
dc.contributor.uportoFaculdade de Engenharia
dc.subject.fosCiências médicas e da saúde::Ciências da saúde
dc.subject.fosMedical and Health sciences::Health sciences
Appears in Collections:FEUP - Artigo em Livro de Atas de Conferência Internacional

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