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https://hdl.handle.net/10216/103087| Author(s): | Joana A. Loureiro Manuel A. N. Coelho Sandra Rocha Maria do Carmo Pereira |
| Title: | Design of potential therapeutic peptides and carriers to inhibit amyloid beta peptide aggregation |
| Issue Date: | 2012 |
| Abstract: | The conformational changes and aggregation of amyloid beta peptide (A beta) are associated to Alzheimer's disease (AD). The aim of this work is to study the structure and fibril assembly of A beta in the presence of charged and nonionic amphiphiles, and beta-sheet breaker peptides/conjugates. It is expected that these molecules will inhibit A beta aggregation. Liposome systems will be developed as carriers for these peptide conjugates to cross the brain blood barrier (BBB). |
| Subject: | Biotecnologia ambiental Environmental biotechnology |
| Scientific areas: | Ciências da engenharia e tecnologias::Biotecnologia ambiental Engineering and technology::Environmental biotechnology |
| URI: | https://repositorio-aberto.up.pt/handle/10216/103087 |
| Source: | 2012 IEEE 2ND PORTUGUESE MEETING IN BIOENGINEERING (ENBENG) |
| Document Type: | Artigo em Livro de Atas de Conferência Internacional |
| Rights: | restrictedAccess |
| Appears in Collections: | FEUP - Artigo em Livro de Atas de Conferência Internacional |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 90258.pdf Restricted Access | 86.46 kB | Adobe PDF | Request a copy from the Author(s) |
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