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Author(s): M. Eduarda Silva
Teresa Mendonça
Isabel Silva
Hugo Magalhães
Title: Statistical analysis of neuromuscular blockade response: contributions to an automatic controller calibration
Issue Date: 2005
Abstract: Muscle relaxant drugs are currently given during surgical operations. The design of controllers for the automatic control of neuromuscular blockade benefits from an individual tuning of the controller to the characteristics of the patient. A novel approach to the characterization of the neuromuscular blockade response induced by an initial bolus at the beginning of anaesthesia is proposed. This approach is based on the statistical analysis of the data using principal components and Walsh-Fourier spectral analysis. These methods provide information about the patients dynamics, allowing the on-line autocalibration of the controller, using multiple linear regression techniques. Observed and simulated data are used to compare different approaches to the characterization of the bolus response.
Subject: Estatística, Ciências da computação e da informação
Statistics, Computer and information sciences
Scientific areas: Ciências exactas e naturais::Ciências da computação e da informação
Natural sciences::Computer and information sciences
Document Type: Artigo em Revista Científica Internacional
Rights: restrictedAccess
Appears in Collections:FCUP - Artigo em Revista Científica Internacional
FEUP - Artigo em Revista Científica Internacional

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