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Author(s): Paula Araújo
Madalena Lemos
Filipe Mergulhão
Luís Melo
Manuel José Simões
Title: Antimicrobial resistance to disinfectants in biofilms
Issue Date: 2011
Abstract: Microorganisms have a natural capacity to attach to surfaces, to multiply and to embed themselves in a slimy matrix,forming biofilms. These allow complex interactions among different species and surfaces. There is significant evidencethat bacterial growth in attached communities constituted the first form of life on the planet, and it is estimated that themajority of microbial activity on earth is resultant from biofilms, rather than microbes growing isolated in the form ofplanktonic cells. Industrial units, particularly food processing plants, provide good environmental conditions for biofilmproliferation, such as an abundant source of nutrients, which can create a significant problem mainly because most of thesemicroorganisms can be pathogens. Therefore, cleaning and disinfection in food processing plants are important issues thatdeserve full consideration. However, the phenotype of biofilms provides intrinsic resistance to cleaning and disinfection.Nowadays, there are no biofilm control strategies that inactivate, remove or prevent their regrowth after antimicrobialtreatment.This study provides information on the problems of biofilm formation and on the main strategies used for theircontrol. Information on the antimicrobial mode of action of biocides and biofilm resistance mechanisms is also provided.
Subject: Biotecnologia industrial
Industrial biotechnology
Scientific areas: Ciências da engenharia e tecnologias::Biotecnologia industrial
Engineering and technology::Industrial biotechnology
Source: Science Against Microbial Pathogens: Communicating Current Research and Technological Advances
Document Type: Capítulo ou Parte de Livro
Rights: restrictedAccess
Appears in Collections:FEUP - Capítulo ou Parte de Livro

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