Impacto da Cannabis ao nível do funcionamento cerebral: meta-análise dos Estudos de Imagiologia Cerebral

Abstract

Cannabis has been associated with brain function disorders, with brain activation diminished in Cannabis users. The present metaanalysis was conducted from six imaging studies, in order to investigate Cannabis influence in the CBF (cerebral blood flow). The effect size (Cohen's d) was calculated for each study in order to find the medium effect size of Cannabis use in the CBF in relation to variable considered. The results show a small negative impact of Cannabis use in the cortex activation map, particularly in the occipital and parietal lobes, and a small positive impact in the pre-frontal cortex. The sample's small size is the major limitation of the study.