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|Title:||Revisiting the Female Germline and Its Expanding Toolbox|
|Abstract:||The Arabidopsis thaliana ovule arises as a female reproductive organ composed solely of somatic diploid cells. Among them, one cell will acquire a unique identity and initiate female germline development. In this review we explore the complex network that facilitates differentiation of this single cell, and consider how it becomes committed to a distinct developmental program. We highlight recent progress towards understanding the role of intercellular communication, cell competency, and cell-cycle regulation in the ovule primordium, and we discuss the possibility that distinct pathways restrict germline development at different stages. Importantly, these recent findings suggest a renaissance in plant ovule research, restoring the female germline as an attractive model to study cell communication and cell fate establishment in multicellular organs.|
|Document Type:||Outra Publicação em Revista Científica Internacional|
|Appears in Collections:||FCUP - Outra Publicação em Revista Científica Internacional|
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|407852.pdf||Revisiting the female germline...||7.42 MB||Adobe PDF|
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