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https://hdl.handle.net/10216/119039
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DC Field | Value | Language |
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dc.creator | Magalhães, A | |
dc.creator | Duarte, HO | |
dc.creator | Reis, CA | |
dc.date.accessioned | 2019-02-21T12:16:20Z | - |
dc.date.available | 2019-02-21T12:16:20Z | - |
dc.date.issued | 2017 | |
dc.identifier.issn | 1535-6108 | |
dc.identifier.uri | https://hdl.handle.net/10216/119039 | - |
dc.description.abstract | Glycosylation alterations are involved in several steps of human cancer pathogenesis. In this issue of Cancer Cell, Agrawal et al. identified the glycosyltransferase FUT8 as a previously unrecognized mediator of melanoma metastasis, establishing core fucosylation as a potential therapeutic target for prevention and treatment of metastatic tumors. | |
dc.description.sponsorship | The authors acknowledge funding by FEDER, COMPETE and FCT: POCI-01-0145-FEDER-007274 (UID/BIM/04293/2013), POCI-01-0145-FEDER-016585 (PTDC/BBB-EBI/0567/2014), NORTE 2020 (NORTE-01-0145-FEDER-000029), and EU 7th Framework Programme ITN 316929. | |
dc.language.iso | eng | |
dc.publisher | Elsevier (Cell Press) | |
dc.relation | info:eu-repo/grantAgreement/FCT/5876/147342/PT | |
dc.relation.ispartof | Cancer Cell, vol.31(6), p. 733-735 | |
dc.rights | openAccess | |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.subject | Fucose | |
dc.subject | Fucosyltransferases | |
dc.subject | Glycosylation | |
dc.subject | Humans | |
dc.subject | Melanoma | |
dc.subject | Neoplasm Metastasis | |
dc.subject | Skin Neoplasms | |
dc.title | Aberrant Glycosylation in Cancer: A Novel Molecular Mechanism Controlling Metastasis | |
dc.type | Outra Publicação em Revista Científica Internacional | |
dc.contributor.uporto | Instituto de Investigação e Inovação em Saúde | |
dc.identifier.doi | 10.1016/j.ccell.2017.05.012 | |
dc.relation.publisherversion | https://www.sciencedirect.com/science/article/pii/S1535610817302088?via%3Dihub | |
Appears in Collections: | I3S - Outra Publicação em Revista Científica Internacional |
Files in This Item:
File | Description | Size | Format | |
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Magalhaes_Cancer_Cell_2017.pdf | 514.43 kB | Adobe PDF | View/Open |
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