Please use this identifier to cite or link to this item:
https://hdl.handle.net/10216/119039
Author(s): | Magalhães, A Duarte, HO Reis, CA |
Title: | Aberrant Glycosylation in Cancer: A Novel Molecular Mechanism Controlling Metastasis |
Publisher: | Elsevier (Cell Press) |
Issue Date: | 2017 |
Abstract: | Glycosylation alterations are involved in several steps of human cancer pathogenesis. In this issue of Cancer Cell, Agrawal et al. identified the glycosyltransferase FUT8 as a previously unrecognized mediator of melanoma metastasis, establishing core fucosylation as a potential therapeutic target for prevention and treatment of metastatic tumors. |
Subject: | Fucose Fucosyltransferases Glycosylation Humans Melanoma Neoplasm Metastasis Skin Neoplasms |
URI: | https://hdl.handle.net/10216/119039 |
Source: | Cancer Cell, vol.31(6), p. 733-735 |
Related Information: | info:eu-repo/grantAgreement/FCT/5876/147342/PT |
Document Type: | Outra Publicação em Revista Científica Internacional |
Rights: | openAccess |
License: | http://creativecommons.org/licenses/by-nc-nd/4.0/ |
Appears in Collections: | I3S - Outra Publicação em Revista Científica Internacional |
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Magalhaes_Cancer_Cell_2017.pdf | 514.43 kB | Adobe PDF | View/Open |
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