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Author(s): Berta N. Estevinho
Rita Mota
José P. Leite
Paula Tamagnini
Luís Gales
Fernando Rocha
Title: Application of a cyanobacterial extracellular polymeric substance in the microencapsulation of vitamin B12
Issue Date: 2019
Abstract: The cyanobacterial extracellular polymeric substances (EPS) are heteropolysaccharides that possess characteristics suitable for food and pharmaceutical applications. In this work, an extracellular carbohydrate polymer isolated from the marine cyanobacterium Cyanothece sp. CCY 0110, alone or combined with arabic gum, was tested for the microencapsulation of the vitamin B12, the most chemically complex and the largest molecule among all the vitamins. The incorporation of vitamins into food systems can provide a simple way to develop new functional foods. The microencapsulation by a spray-drying process and the controlled release of vitamin B12 were studied. Arabic gum and cyanobacterial polymer or only cyanobacterial polymer were used as encapsulating agents. The microparticles obtained were evaluated and characterized in terms of morphology, size and release profiles. Spherical microparticles with a very rough surface were obtained. The microparticles prepared only with cyanobacterial polymer presented a mean diameter of approximately 8 m, while the ones prepared with cyanobacterial polymer and arabic gum presented a smaller size. The main kinetic release models (zero and first order kinetics and the Higuchi, Korsmeyer-Peppas and Weibull models) were adjusted to the experimental release profiles. The model that best describes the release profile for the microparticles prepared with cyanobacterial polymer is the kinetics of first order, while for the ones prepared with cyanobacterial polymer and arabic gum, the Weibull model presents the best fit to the experimental values. (c) 2018
Related Information: info:eu-repo/grantAgreement/FCT - Fundação para a Ciência e Tecnologia/P2020|COMPETE - Projetos em Todos os Domínios Científicos/POCI-01-0145-FEDER-028715/Desenvolvimento de sistemas funcionais de libertação controlada por microencapsulação de compostos ativos e naturais, com interesse terapêutico, nutricional e tecnológico/ MicroDelivery
info:eu-repo/grantAgreement/FCT - Fundação para a Ciência e Tecnologia/Projetos Estratégicos/UID/EQU/00511/2013 - POCI-01-0145-FEDER-006939/Laboratório de Engenharia de Processos, Ambiente, Biotecnologia e Energia/LEPABE
info:eu-repo/grantAgreement/Comissão de Coordenação e Desenvolvimento Regional do Norte/P2020|Norte2020-Projetos Integrados ICDT/NORTE-01-0145-FEDER-000005/LEPABE-2-ECO-INNOVATION/LEPABE-2-ECO-INNOVATION
Document Type: Artigo em Revista Científica Internacional
Rights: restrictedAccess
Appears in Collections:FCUP - Artigo em Revista Científica Internacional
FEUP - Artigo em Revista Científica Internacional

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