Please use this identifier to cite or link to this item:
https://hdl.handle.net/10216/118485
Author(s): | Pombinho, R Sousa, S Cabanes, D |
Title: | Scavenger Receptors: Promiscuous Players during Microbial Pathogenesis |
Publisher: | CRC Press |
Issue Date: | 2018-11-30 |
Abstract: | Innate immunity is the most broadly effective host defense, being essential to clear the majority of microbial infections. Scavenger Receptors comprise a family of sensors expressed in a multitude of host cells, whose dual role during microbial pathogenesis gained importance over recent years. SRs regulate the recruitment of immune cells and control both host inflammatory response and bacterial load. In turn, pathogens have evolved different strategies to overcome immune response, avoid recognition by SRs and exploit them to favor infection. Here, we discuss the most relevant findings regarding the interplay between SRs and pathogens, discussing how these multifunctional proteins recognize a panoply of ligands and act as bacterial phagocytic receptors. |
Subject: | Innate immune response Microbial pathogenesis Pathogens Scavenger receptors |
URI: | https://repositorio-aberto.up.pt/handle/10216/118485 |
Series: | Critical reviews in microbiology, vol. 44(6), p. 685-700 |
Related Information: | info:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBD%2F89542%2F2012/PT |
Document Type: | Artigo em Revista Científica Internacional |
Rights: | embargoedAccess |
Embargo End Date: | 2019-11-30 |
Appears in Collections: | I3S - Artigo em Revista Científica Internacional |
Files in This Item:
File | Description | Size | Format | |
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10.1080 1040841X.2018.1493716.pdf | 8.36 MB | Adobe PDF | ![]() View/Open |
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