Please use this identifier to cite or link to this item: https://hdl.handle.net/10216/104338
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dc.creatorA. Catarina Guedes
dc.creatorMaria S. Gião
dc.creatorRui Seabra
dc.creatorA. C. Silva Ferreira
dc.creatorPaula Tamagnini
dc.creatorPedro Moradas Ferreira
dc.creatorF. Xavier Malcata
dc.date.accessioned2019-02-08T15:13:36Z-
dc.date.available2019-02-08T15:13:36Z-
dc.date.issued2013
dc.identifier.issn1660-3397
dc.identifier.othersigarra:70165
dc.identifier.urihttps://repositorio-aberto.up.pt/handle/10216/104338-
dc.description.abstractA growing market for novel antioxidants obtained from non-expensive sources justifies educated screening of microalgae for their potential antioxidant features. Characterization of the antioxidant profile of 18 species of cyanobacteria (prokaryotic microalgae) and 23 species of (eukaryotic) microalgae is accordingly reported in this paper. The total antioxidant capacity, accounted for by both water-and lipid-soluble antioxidants, was evaluated by the (radical cation) ABTS method. For complementary characterization of cell extracts, a deoxyribose assay was carried out, as well as a bacteriophage P22/Salmonella-mediated approach. The microalga Scenedesmus obliquus strain M2-1 exhibited the highest (p > 0.05) total antioxidant capacity (149 +/- 47 AAU) of intracellular extracts. Its scavenger activity correlated well with its protective effects against DNA oxidative damage induced by copper(II)-ascorbic acid; and against decay in bacteriophage infection capacity induced by H2O2. Finally, performance of an Ames test revealed no mutagenic effects of the said extract.
dc.language.isoeng
dc.rightsrestrictedAccess
dc.subjectMedicina básica
dc.subjectBasic medicine
dc.titleEvaluation of the antioxidant activity of cell extracts from microalgae
dc.typeArtigo em Revista Científica Internacional
dc.contributor.uportoFaculdade de Engenharia
dc.contributor.uportoInstituto de Ciências Biomédicas Abel Salazar
dc.contributor.uportoFaculdade de Ciências
dc.identifier.doi10.3390/md11041256
dc.identifier.authenticusP-005-1X4
dc.subject.fosCiências médicas e da saúde::Medicina básica
dc.subject.fosMedical and Health sciences::Basic medicine
Appears in Collections:FCUP - Artigo em Revista Científica Internacional
FEUP - Artigo em Revista Científica Internacional
ICBAS - Artigo em Revista Científica Internacional

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