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dc.creatorSílvia C. Pinho
dc.creatorOlga C. Nunes
dc.creatorAlexandre Lobo da Cunha
dc.creatorManuel F. Almeida
dc.description.abstractAlthough alkaline hydrolysis treatment emerges as an alternative disinfection/sterilization method for medical waste, information on its effects on the inactivation of biological indicators is scarce. The effects of alkaline treatment on the resistance of Geobacillus stearothermophilus spores were investigated and the influence of temperature (80 degrees C, 100 degrees C and 110 degrees C) and NaOH concentration was evaluated. In addition, spore inactivation in the presence of animal tissues and discarded medical components, used as surrogate of medical waste, was also assessed. The effectiveness of the alkaline treatment was carried out by determination of survival curves and D-values. No significant differences were seen in D-values obtained at 80 degrees C and 100 degrees C for NaOH concentrations of 0.5 M and 0.75 M. The D-values obtained at 110 degrees C (2.3-0.5 min) were approximately 3 times lower than those at 100 degrees C (8.8-1.6 min). Independent of the presence of animal tissues and discarded medical components, 6 log10 reduction times varied between 66 and 5 min at 100 degrees C-0.1 M NaOH and 110 degrees C-1 M NaOH, respectively. The alkaline treatment may be used in future as a disinfection or sterilization alternative method for contaminated waste.
dc.relationinfo:eu-repo/grantAgreement/FCT - Fundação para a Ciência e Tecnologia/Projectos de I&DT em Todos os Domínios Científicos/PTDC/SAU-SAP/114855/2009/Hidrólise alcalina de resíduos hospitalares infecciosos/PTDC/SAU-SAP/114855/2009
dc.relationinfo:eu-repo/grantAgreement/FCT - Fundação para a Ciência e Tecnologia/Projetos Estratégicos/UID/EQU/00511/2013 - POCI-01-0145-FEDER-006939/Laboratório de Engenharia de Processos, Ambiente, Biotecnologia e Energia/LEPABE
dc.subjectBiologia ambiental, Tecnologia ambiental, Engenharia do ambiente, Ciências biológicas
dc.subjectEnvironmental biology, Environmental technology, Environmental engineering, Biological sciences
dc.titleInactivation of Geobacillus stearothermophilus spores by alkaline hydrolysis applied to medical waste treatment
dc.typeArtigo em Revista Científica Internacional
dc.contributor.uportoFaculdade de Engenharia
dc.subject.fosCiências da engenharia e tecnologias::Engenharia do ambiente
dc.subject.fosEngineering and technology::Environmental engineering
dc.subject.fosCiências exactas e naturais::Ciências biológicas
dc.subject.fosNatural sciences::Biological sciences
Appears in Collections:FEUP - Artigo em Revista Científica Internacional

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