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Author(s): Patrícia J. M. Reis
Ana C. Reis
Benjamin Ricken
Boris A. Kolvenbach
Célia M. Manaia
Philippe F. X. Corvini
Olga C. Nunes
Title: Biodegradation of sulfamethoxazole and other sulfonamides by Achromobacter denitrificans PR1
Issue Date: 2014
Abstract: This study aimed to isolate and characterize a microbial culture able to degrade sulfonamides. Sulfamethoxazole (SMX)-degrading microorganisms were enriched from activated sludge and wastewater. The resultant mixed culture was composed of four bacterial strains, out of which only Achromobacter denitrificans PR1 could degrade SMX. This sulfonamide was used as sole source of carbon, nitrogen and energy with stoichiometric accumulation of 3-amino-5-methylisoxazole. Strain PR1 was able to remove SMX at a rate of 73.6 +/- 9.6 mu mol(SMX)/g(cell) (dry) (weight) h. This rate more than doubled when a supplement of amino acids or the other members of the mixed culture were added. Besides SMX, strain PR1 was able to degrade other sulfonamides with anti-microbial activity. Other environmental Achromobacter spp. could not degrade SMX, suggesting that this property is not broadly distributed in members of this genus. Further studies are needed to shed additional light on the genetics and enzymology of this process.
Subject: Engenharia civil
Civil engineering
Scientific areas: Ciências da engenharia e tecnologias::Engenharia civil
Engineering and technology::Civil engineering
Related Information: info:eu-repo/grantAgreement/FCT - Fundação para a Ciência e Tecnologia/Projectos de I&DT em Todos os Domínios Científicos/PTDC/AAC-AMB/113091/2009/Eliminação de micropoluentes com actividade antimicrobiana de águas residuais/PTDC/AAC-AMB/113091/2009
Document Type: Artigo em Revista Científica Internacional
Rights: restrictedAccess
Appears in Collections:FEUP - Artigo em Revista Científica Internacional

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