Please use this identifier to cite or link to this item:
https://hdl.handle.net/10216/102601
Author(s): | Patrícia J. M. Reis Ana C. Reis Benjamin Ricken Boris A. Kolvenbach Célia M. Manaia Philippe F. X. Corvini Olga C. Nunes |
Title: | Biodegradation of sulfamethoxazole and other sulfonamides by Achromobacter denitrificans PR1 |
Issue Date: | 2014 |
Abstract: | This study aimed to isolate and characterize a microbial culture able to degrade sulfonamides. Sulfamethoxazole (SMX)-degrading microorganisms were enriched from activated sludge and wastewater. The resultant mixed culture was composed of four bacterial strains, out of which only Achromobacter denitrificans PR1 could degrade SMX. This sulfonamide was used as sole source of carbon, nitrogen and energy with stoichiometric accumulation of 3-amino-5-methylisoxazole. Strain PR1 was able to remove SMX at a rate of 73.6 +/- 9.6 mu mol(SMX)/g(cell) (dry) (weight) h. This rate more than doubled when a supplement of amino acids or the other members of the mixed culture were added. Besides SMX, strain PR1 was able to degrade other sulfonamides with anti-microbial activity. Other environmental Achromobacter spp. could not degrade SMX, suggesting that this property is not broadly distributed in members of this genus. Further studies are needed to shed additional light on the genetics and enzymology of this process. |
Subject: | Engenharia civil Civil engineering |
Scientific areas: | Ciências da engenharia e tecnologias::Engenharia civil Engineering and technology::Civil engineering |
URI: | https://hdl.handle.net/10216/102601 |
Related Information: | info:eu-repo/grantAgreement/FCT - Fundação para a Ciência e a Tecnologia/Projectos de I&DT em Todos os Domínios Científicos/PTDC/AAC-AMB/113091/2009/Eliminação de micropoluentes com actividade antimicrobiana de águas residuais/PTDC/AAC-AMB/113091/2009 |
Document Type: | Artigo em Revista Científica Internacional |
Rights: | restrictedAccess |
Appears in Collections: | FEUP - Artigo em Revista Científica Internacional |
Files in This Item:
File | Description | Size | Format | |
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104757.pdf Restricted Access | Artigo original publicado | 1.14 MB | Adobe PDF | Request a copy from the Author(s) |
104757.1.pdf | Post-Print version | 1.28 MB | Adobe PDF | View/Open |
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