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Author(s): Luísa Pereira
Farida Alshamali
Rune Andreassen
Ruth Ballard
Wasun Chantratita
Nam Soo Cho
Clotilde Coudray
Jean-Michel Dugoujon
Marta Espinoza
Fabricio González-Andrade
Sibte Hadi
Uta-Dorothee Immel
Nina Jeran
Dubravka Havas
Catalin Marian
Antonio Gonzalez-Martin
Gerhard Mertens
Walther Parson
Carlos Perone
Lourdes Prieto
Haruo Takeshita
Héctor Rangel Villalobos
Zhaoshu Zeng
Lev Zhivotovsky
Rui Camacho
Nuno A. Fonseca
Title: PopAffiliator: online calculator for individual affiliation to a major population group based on 17 autosomal STR genotype profile
Issue Date: 2011
Abstract: Because of their sensitivity and high level of discrimination, short tandem repeat (STR) maker systems are currently the method of choice in routine forensic casework and data banking, usually in multiplexes up to15-17 loci. Constraints related to sample amount and quality, frequently encountered in forensic casework, willnot allow to change this picture in the near future, notwithstanding the technological developments. In thisstudy, we present a free online calculator named PopAffiliator ( for individual population affiliation in the three main population groups, Eurasian, East Asian and sub-Saharan African, based ongenotype profiles for the common set of STRs used inforensics. This calculator performs affiliation based on amodel constructed using machine learning techniques. Themodel was constructed using a data set of approximatelyfifteen thousand individuals collected for this work. Theaccuracy of individual population affiliation is approximately86%, showing that the common set of STRs routinely used in forensics provide a considerable amount of information for population assignment, in addition to being excellent for individual identification.
Subject: Ciências biológicas, Ciências biológicas
Biological sciences, Biological sciences
Scientific areas: Ciências exactas e naturais::Ciências biológicas
Natural sciences::Biological sciences
Document Type: Artigo em Revista Científica Internacional
Rights: restrictedAccess
Appears in Collections:FEUP - Artigo em Revista Científica Internacional

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