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Author(s): Rui Pedro Menezes da Rosa Neves
Title: Lymphatic Filariasis detection in microscopic images
Issue Date: 2016-07-14
Abstract: In Africa, the propagation of parasites like the lymphatic filariasis is complicatingseriously the efforts of health professionals to cure certain diseases. Although there aremedicines capable to treat the lymphatic filariasis, this needs to be discovered firstly which isnot always an easy task having into account that in most countries affected by this disease it canonly be detected at night (nocturne). The lymphatic filariasis is then, a parasitical infectionwhich can originate changes or ruptures in the lymphatic system as well as an abnormal growthof certain areas of the body causing pain, incapacity and social stigma.Approximately 1.23 billion people in 58 countries from all over the world are threatenedby this disease which requires a preventive treatment to stop its propagation which makes iteven more important for the existence of a mechanism that is less costly and more agile in theanalysis of a blood smear to verify the existence of microfilariae (little worms that are producedby other adult worms while housed in the lymphatic system).The lymphatic filariasis is caused by an infection with nematodes ("roundworms") of theFilariodidea family in which three types are inserted: Wuchereria Bancroft, responsible for 90%of all cases; Brugia Malayi, responsible for almost every remaining; B.Timori also causing thedisease. All three have characteristics that can differentiate them which allow them to beidentified.The current identification process of the disease consists on the analysis of microfilariae ina blood smear with a blood sample through a microscope and its identification by the observer.Taking this into account, it is intended to develop image analysis and processingtechniques for the recognition and counting of the two principal types of filarial worms from athin blood smear, a smartphone and a portable microscope making the detection possiblewithout the need of a health professional and consequent automation of the process. To makethis possible an adapter smartphone-microscope can be used to obtain an image with themagnification of 40x3. The images can then be analyzed in a server or in the smartphone, if ithas enough processing for it. It is expected from this process that the need to resort to labs toprocess the blood smear gets fulfilled making the process more accessible and agile instead ofcostly and slow.For the detection of the parasites from the acquired images it is intended to implement,experiment and choose the more adequate operations. These comprise pre-processing operationswith the goal to enhance the acquired images and eliminate possible artifacts prevenient fromthe acquisition system. However, the principal operations should be those that allow theverification of existence or nonexistence, recognition and classification of the pretendedparasites. Processing and analysis techniques that are common in these processes are based inthe extraction of features (e.g. SIRF, SURF, and FLANN) template similarity, edge detectionand description of contours and recognition of statistical patterns.Once detected and recognized one or more parasites and its types should be defined andused a rule to declare the presence of the disease and its stage.
Subject: Engenharia electrotécnica, electrónica e informática
Electrical engineering, Electronic engineering, Information engineering
Scientific areas: Ciências da engenharia e tecnologias::Engenharia electrotécnica, electrónica e informática
Engineering and technology::Electrical engineering, Electronic engineering, Information engineering
TID identifier: 201319772
Document Type: Dissertação
Rights: openAccess
Appears in Collections:FEUP - Dissertação

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