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dc.creatorBarros-Carvalho, A
dc.creatorMorais-de-Sá, E
dc.date.accessioned2025-02-26T18:53:48Z-
dc.date.available2025-02-26T18:53:48Z-
dc.date.issued2022
dc.identifier.issn0021-9525
dc.identifier.urihttps://hdl.handle.net/10216/165545-
dc.description.abstractHow cells spatially organize their plasma membrane, cytoskeleton, and cytoplasm remains a central question for cell biologists. In this issue of JCB, Calvi et al. (2022. J. Cell Biol. https://doi.org/10.1083/jcb.202201048) identify PP1 phosphatases as key regulators of C. elegans anterior–posterior polarity, by counterbalancing aPKC-mediated phosphorylation of PAR-2.
dc.description.sponsorshipWork in the E. Morais-de-Sá lab is supported by FCT—Fundação para a Ciˆencia e a Tecnologia, I.P., under the project PTDC/BIA-CEL/1511/2021. A. Barros-Carvalho is supported by a PhD fellowship from FCT (2021.07215.BD).
dc.language.isoeng
dc.publisherRockefeller University Press
dc.relationinfo:eu-repo/grantAgreement/FCT/3599-PPCDT/PTDC%2FBIA-CEL%2F1511%2F2021/PT
dc.relationinfo:eu-repo/grantAgreement/FCT/POR_NORTE/2021.07215.BD/PT
dc.relation.ispartofJournal of Cell Biology, vol.221(10):e202208008
dc.rightsopenAccess
dc.rights.urihttps://creativecommons.org/licenses/by-nc-sa/4.0/
dc.subject.meshAnimals
dc.subject.meshCaenorhabditis elegans Proteins / metabolismo
dc.subject.meshCaenorhabditis elegans / cytology
dc.subject.meshCaenorhabditis elegans / enzymology
dc.subject.meshCell Membrane
dc.subject.meshCell Polarity
dc.subject.meshCytoplasm
dc.subject.meshMicrotubules / metabolism
dc.subject.meshPhosphoprotein Phosphatases / metabolism
dc.subject.meshPhosphorylation
dc.subject.meshProtein Kinase C/ metabolism
dc.titleBalancing cell polarity PARts through dephosphorylation
dc.typeArtigo em Revista Científica Internacional
dc.contributor.uportoInstituto de Investigação e Inovação em Saúde
dc.identifier.doi10.1083/jcb.202208008
dc.relation.publisherversionhttps://rupress.org/jcb/article/221/10/e202208008/213477/Balancing-cell-polarity-PARts-through
Appears in Collections:I3S - Artigo em Revista Científica Internacional

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