Evaluating the potential of natural polymers for water-dispersible curcumin-based solid dispersion colourant systems for food applications

Abstract

Solid dispersion (SD) technology, a strategy through which a hydrophobic compound is molecularly dispersed into a hydrophilic carrier, is raising interest in food applications to surpass natural colourants' low water solubility. Motivated by the importance of using natural solutions, five natural polymers (k-carrageenan (KC), maltodextrin (MD), Arabic gum (AG), potato starch (PS), and pectin (PC) were evaluated against the synthetic benchmark polyvinylpyrrolidone (PVP)). Targeting a stable yellow hue, pH 6 was used, and the effect of salt addition on crystallinity was evaluated. Comparatively with PVP, used as a synthetic polymer reference, SDs based on MD, AG, and PC presented a deeper orange shade. Similar size distributions were achieved for the produced samples except for PS -based SDs, which showed higher sizes in volume. For all systems, polymercurcumin hydrogen bonding was perceptible and reflected in the curcumin crystallinity modification/reduction, particularly if produced under natural pH conditions. The water solubility was significantly improved compared to free curcumin, from 1 mu g/mL to 25-37 mu g/mL (pH 6, PVP - 24.54 mu g/mL) and 18-86 mu g/mL (without pH control, PVP - 28.34 mu g/mL), highlighting the favourable effect of natural polymers.