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Author(s): Morais, S
Costa, AR
Lopes-Conceicao, L
Brandao, M
Borges, M
Araujo, N
Dias, T
Fontes, F
Pereira, S
Lunet, N
Title: Treatment and Other Healthcare Use of Breast Cancer Patients With a Previous Cancer Diagnosis
Publisher: International Institute of Anticancer Research
Issue Date: 2020
Abstract: Background/Aim: To quantify the association between a previous cancer diagnosis and healthcare use among breast cancer (BC) patients, and estimate five-year recurrence-free survival (RFS). Patients and Methods: Women with BC were classified according to a previous cancer diagnosis (BC or other). Healthcare use during the first year and five-year RFS were obtained through clinical and administrative records. Adjusted odds ratios and hazard ratios (HR) were estimated. Results: Among 681 BC patients, 21 had a previous BC and 32 a previous non-BC. The latter were less likely to receive anthracycline-based combination chemotherapy. The former had higher odds of mastectomy and genetic testing. Five-year RFS HRs (95% confidence interval) were 2.75 (0.79-9.52) and 0.52 (0.07-3.89) for previous BC and non-BC, respectively. Conclusion: Previous cancer was associated with less anthracycline-based combination chemotherapy, and patients were more likely to undergo mastectomy and genetic testing. These findings highlight the need for assessment of previous treatments, personal genetic risk and current BC characteristics.
Subject: Breast neoplasm
healthcare use
second primary neoplasms
Source: Anticancer Res. 2020 Feb;40(2):1041-1048
Related Information: info:eu-repo/grantAgreement/FCT/9471 - RIDTI/PTDC/DTP-EPI/7183/2014/PT
info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UID/DTP/04750/2019/PT
info:eu-repo/grantAgreement/FCT/9471 - RIDTI/PTDC/SAU-EPI/32358/2017/PT
Document Type: Artigo em Revista Científica Internacional
Rights: restrictedAccess
Appears in Collections:ISPUP - Artigo em Revista Científica Internacional

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