1. Repositório Aberto da Universidade do Porto
  2. ICBAS - Instituto de Ciências Biomédicas Abel Salazar
  3. ICBAS - Artigo em Revista Científica Internacional
Please use this identifier to cite or link to this item: https://hdl.handle.net/10216/142507
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dc.creatorSharifi-Rad, J
dc.creatorRodrigues, CF
dc.creatorSharopov, F
dc.creatorDocea, AO
dc.creatorKaraca, AC
dc.creatorSharifi-Rad, M
dc.creatorKarincaoglu, DK
dc.creatorGülseren, G
dc.creatorSenol, E
dc.creatorDemircan, E
dc.creatorTaheri, Y
dc.creatorSuleria, HAR
dc.creatorÖzçelik, B
dc.creatorKasapoglu, KN
dc.creatorGültekin-Özgüven, M
dc.creatorDaskaya-Dikmen, C
dc.creatorCho, WC
dc.creatorMartins, N
dc.creatorCalina, D
dc.date.accessioned2022-08-01T11:21:47Z-
dc.date.available2022-08-01T11:21:47Z-
dc.date.issued2020
dc.identifier.issn1661-7827
dc.identifier.urihttps://hdl.handle.net/10216/142507-
dc.description.abstractHeart and blood vessels disorders comprise one of the main causes of death worldwide. Pharmacologically active natural compounds have been used as a complementary therapy in cardiovascular disease around the world in a traditional way. Dietary, natural bioactive compounds, as well as healthy lifestyles, are considered to prevent coronary artery diseases. Pre-clinical and clinical studies reported that consumption of plant-food bioactive derivatives including polyphenolic compounds, peptides, oligosaccharides, vitamins, unsaturated fatty acids possess protective effects on cardiovascular diseases. This review aims to summarize the cardiovascular risk factors, pre-clinical studies and clinical trials related to cardioprotective properties of the plant-food-derived bioactive compounds. Molecular mechanisms by the natural bioactive compounds exert their cardiovascular protective properties have also been highlighted.
dc.description.sponsorshipAcknowledgments: N. Martins would like to thank the Portuguese Foundation for Science and Technology (FCT–Portugal) for the Strategic project ref. UID/BIM/04293/2013 and “NORTE2020 - Programa Operacional Regional do Norte” (NORTE-01-0145-FEDER-000012) and C. F. Rodrigues for the UID/EQU/00511/2019 Project—Laboratory of Process Engineering, Environment, Biotechnology, and Energy—LEPABE financed by national funds through FCT/MCTES (PIDDAC). N. Martins would like to thank the Portuguese Foundation for Science and Technology (FCT-Portugal) for the Strategic project ref. UID/BIM/04293/2013 and ?NORTE2020 - Programa Operacional Regional do Norte? (NORTE-01-0145-FEDER-000012) and C. F. Rodrigues for the UID/EQU/00511/2019 Project-Laboratory of Process Engineering, Environment, Biotechnology, and Energy-LEPABE financed by national funds through FCT/MCTES (PIDDAC).
dc.language.isoeng
dc.publisherMDPI
dc.relation.ispartofInternational Journal of Environmental Research and Public Health, vol.17(7):2326
dc.rightsopenAccess
dc.subject.meshCardiovascular Diseases / physiopathology
dc.subject.meshClinical Trials as Topic
dc.subject.meshDiet
dc.subject.meshHumans
dc.subject.meshLife Style
dc.subject.meshPlants, Edible
dc.titleDiet, lifestyle and cardiovascular diseases: Linking pathophysiology to cardioprotective effects of natural bioactive compounds
dc.typeArtigo em Revista Científica Internacional
dc.contributor.uportoInstituto de Investigação e Inovação em Saúde
dc.identifier.doi10.3390/ijerph17072326
dc.relation.publisherversionhttps://www.mdpi.com/1660-4601/17/7/2326
Appears in Collections:ICBAS - Artigo em Revista Científica Internacional

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