Apium plants: Beyond simple food and phytopharmacological applications

Salehi, B; Venditti, A; Frezza, C; Yücetepe, A; Altuntas, Ü; Uluata, S; Butnariu, M; Sarac, I; Shaheen, S; Petropoulos, SA; Matthews, KR; Kiliç, CS; Atanassova, M; Adetunji, CO; Ademiluyi, AO; Özçelik, B; Fokou, PVT; Martins, N; Cho, WC; Sharifi-Rad, J

doi:10.3390/app9173547

Please use this identifier to cite or link to this item: https://hdl.handle.net/10216/136262

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DC Field	Value	Language
dc.creator	Salehi, B
dc.creator	Venditti, A
dc.creator	Frezza, C
dc.creator	Yücetepe, A
dc.creator	Altuntas, Ü
dc.creator	Uluata, S
dc.creator	Butnariu, M
dc.creator	Sarac, I
dc.creator	Shaheen, S
dc.creator	Petropoulos, SA
dc.creator	Matthews, KR
dc.creator	Kiliç, CS
dc.creator	Atanassova, M
dc.creator	Adetunji, CO
dc.creator	Ademiluyi, AO
dc.creator	Özçelik, B
dc.creator	Fokou, PVT
dc.creator	Martins, N
dc.creator	Cho, WC
dc.creator	Sharifi-Rad, J
dc.date.accessioned	2021-09-20T10:52:28Z	-
dc.date.available	2021-09-20T10:52:28Z	-
dc.date.issued	2019
dc.identifier.issn	2076-3417
dc.identifier.uri	https://hdl.handle.net/10216/136262	-
dc.description.abstract	Apium plants belong to the Apiaceae family and are included among plants that have been in use in traditional medicine for thousands of years worldwide, including in the Mediterranean, as well as the tropical and subtropical regions of Asia and Africa. Some highlighted medical benefits include prevention of coronary and vascular diseases. Their phytochemical constituents consist of bergapten, flavonoids, glycosides, furanocoumarins, furocoumarin, limonene, psoralen, xanthotoxin, and selinene. Some of their pharmacological properties include anticancer, antioxidant, antimicrobial, antifungal, nematocidal, anti-rheumatism, antiasthma, anti-bronchitis, hepatoprotective, appetizer, anticonvulsant, antispasmodic, breast milk inducer, anti-jaundice, antihypertensive, anti-dysmenorrhea, prevention of cardiovascular diseases, and spermatogenesis induction. The present review summarizes data on ecology, botany, cultivation, habitat, medicinal use, phytochemical composition, preclinical and clinical pharmacological efficacy of Apium plants and provides future direction on how to take full advantage of Apium plants for the optimal benefit to mankind.
dc.description.sponsorship	N. Martins would like to thank the Portuguese Foundation for Science and Technology (FCT-Portugal) for the strategic project ref. UID/BIM/04293/2013 and “NORTE2020-Northern Regional Operational Program” (NORTE-01-0145-FEDER-000012).
dc.language.iso	eng
dc.publisher	MDPI
dc.relation	info:eu-repo/grantAgreement/FCT/5876/147342/PT
dc.relation.ispartof	Applied Sciences (Switzerland), vol.9(17): 3547
dc.rights	openAccess
dc.rights.uri	https://creativecommons.org/licenses/by/4.0/
dc.subject	Apium
dc.subject	Botany
dc.subject	Medicinal use
dc.subject	Pharmacological properties
dc.subject	Phytochemicals
dc.title	Apium plants: Beyond simple food and phytopharmacological applications
dc.type	Artigo em Revista Científica Internacional
dc.contributor.uporto	Instituto de Investigação e Inovação em Saúde
dc.identifier.doi	10.3390/app9173547
dc.relation.publisherversion	https://www.mdpi.com/2076-3417/9/17/3547
Appears in Collections:	I3S - Artigo em Revista Científica Internacional

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