Please use this identifier to cite or link to this item: https://hdl.handle.net/10216/120515
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dc.creatorRibeiro J.
dc.creatorTiritan M.E.
dc.creatorPinto M.M.M.
dc.creatorFernandes C.
dc.date.accessioned2019-05-31T16:16:37Z-
dc.date.available2019-05-31T16:16:37Z-
dc.date.issued2017
dc.identifier.issn20738994
dc.identifier.urihttps://hdl.handle.net/10216/120515-
dc.description.abstractThe development of chiral stationary phases (CSPs) for liquid chromatography (LC) revolutionized the enantioseparation and, nowadays, different types of CSPs are commercially available. Polysaccharide-based CSPs are one of the most versatile and widely used for both analytical and preparative applications and they are able to resolve several classes of racemates. Phenylcarbamates of amylose and cellulose derivatives are the most successful; however, polysaccharide-based CSPs comprising marine-derived polysaccharides are also described revealing high chiral recognition abilities and wider range of mobile phases. A literature survey covering the report on chitin and chitosan based CSPs is presented. The chemical structure of the chiral selectors, their development and applications in chiral LC are emphasized. © 2017 by the authors.
dc.description.sponsorshipAcknowledgments: This work was partially supported through national funds provided by FCT/ MCTES—Foundation for Science and Technology from the Minister of Science, Technology and Higher Education (PIDDAC) and European Regional Development Fund (ERDF) through the COMPETE—Programa Operacional Factores de Competitividade (POFC) programme, under the Strategic Funding UID/Multi/04423/2013, the project PTDC/MAR-BIO/4694/2014 (reference POCI-01-0145-FEDER-016790; Project 3599—Promover a Produção Científica e Desenvolvimento Tecnológico e a Constituição de Redes Temáticas (3599-PPCDT)) in the framework of the programme PT2020 as well as by the project INNOVMAR—Innovation and Sustainability in the Management and Exploitation of Marine Resources (reference NORTE-01-0145-FEDER-000035, within Research Line NOVELMAR), supported by North Portugal Regional Operational Programme (NORTE 2020), under the PORTUGAL 2020 Partnership Agreement, through the European Regional Development Fund (ERDF), and Chiral_Drugs_CESPU_2017.
dc.language.isoeng
dc.publisherMDPI
dc.relationinfo:eu-repo/grantAgreement/FCT/5876/147268/PT
dc.relation.ispartofSymmetry, vol. 9(9):190
dc.rightsopenAccess
dc.titleChiral stationary phases for liquid chromatography based on chitin- and chitosan-derived marine polysaccharides
dc.typeArtigo em Revista Científica Internacional
dc.contributor.uportoCIIMAR - Centro Interdisciplinar de Investigação Marinha e Ambiental
dc.identifier.doi10.3390/sym9090190
dc.relation.publisherversionhttp://dx.doi.org/10.3390/sym9090190
Appears in Collections:CIIMAR - Artigo em Revista Científica Internacional

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