1. Repositório Aberto da Universidade do Porto
  2. CIIMAR - Centro Interdisciplinar de Investigação Marinha e Ambiental
  3. CIIMAR - Artigo em Revista Científica Internacional
Please use this identifier to cite or link to this item: https://hdl.handle.net/10216/120454
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dc.creatorTiritan M.E.
dc.creatorFernandes C.
dc.creatorMaia A.S.
dc.creatorPinto M.
dc.creatorCass Q.B.
dc.date.accessioned2019-05-31T16:15:56Z-
dc.date.available2019-05-31T16:15:56Z-
dc.date.issued2018
dc.identifier.issn219673
dc.identifier.urihttps://hdl.handle.net/10216/120454-
dc.description.abstractThe correct quantification of enantiomers is pivotal in a variety of fields, such as pharmacokinetic studies, enantioselective syntheses, chemical characterization of natural products, authentication of fragrance and food, biodegradation behavior, accurate evaluation of environmental risk, and it can also provide information for sentencing guidance in forensic field. Enantioselective chromatography is the first choice to assess the composition of an enantiomeric mixture. Different notations have been used to express the measured enantiomeric ratios, which compromise the results and represent a challenge for data comparison. This manuscript critically discusses the currently used notations and exemplifies with applications in different fields indicating the advantages and disadvantages of one of the adopted systems. In order to simplify the notations, the use of enantiomeric ratio (e.r.%) as standardization for nonchiroptical methods is proposed. © 2018 Elsevier
dc.description.sponsorshipThis research was partially supported by the Strategic Funding UID/Multi/04423/2013 through national funds provided by FCT—Foundation for Science and Technology and European Regional Development Fund (ERDF) , in the framework of the programme PT2020, the project PTDC/MAR-BIO/4694/2014 (reference POCI-01-0145-FEDER-016790; Project 3599—Promover a Produção Científica e Desenvolvimento Tecnológico e a Constituição de Redes Temáticas (3599-PPCDT)) as well as by the project INNOVMAR—Innovation and Sustainability in the Management and Exploitation of Marine Resources (reference NORTE-01-0145-FEDER-000035, within Research Line NOVELMAR), supported by North Portugal Regional Operational Programme (NORTE 2020), under the PORTUGAL 2020 Partnership Agreement, through the European Regional Development Fund (ERDF), and CHIRALXANT-CESPU-2018. The financial support of São Paulo Research Foundation (FAPESP) , grant 2014/50249-8 , and of the National Council for Scientific and Technological Development (CNPq – Brazil) is also acknowledged.
dc.language.isoeng
dc.publisherElsevier
dc.relationinfo:eu-repo/grantAgreement/FCT/5876/147268/PT
dc.relation.ispartofJournal of Chromatography A, vol. 1569, p. 1-7
dc.rightsrestrictedAccess
dc.subjectBiodegradation
dc.subjectChirality
dc.subjectChromatography
dc.subjectEnantioselectivity
dc.subjectStereochemistry
dc.subjectChemical characterization
dc.subjectEnantiomeric excess
dc.subjectEnantiomeric fractions
dc.subjectEnantiomeric ratio
dc.subjectEnantioselective chromatography
dc.subjectEnantioselective synthesis
dc.subjectEnvironmental risks
dc.subjectPharmacokinetic studies
dc.subjectEnantiomers
dc.subjectfragrance
dc.subjectnatural product
dc.subjectcatalysis
dc.subjectchemical composition
dc.subjectchirality
dc.subjectchromatography
dc.subjectdrug purity
dc.subjectenantiomeric ratio
dc.subjectenantioselectivity
dc.subjectenvironment
dc.subjectfood analysis
dc.subjectforensic science
dc.subjectorganic chemistry
dc.subjectpriority journal
dc.subjectReview
dc.subjectstandardization
dc.subjectsynthesis
dc.subjectchemical analysis
dc.subjectdevices
dc.subjectstandards
dc.subjectstereoisomerism
dc.subjectChemistry Techniques, Analytical
dc.subjectChromatography
dc.subjectStereoisomerism
dc.titleEnantiomeric ratios: Why so many notations?
dc.typeArtigo em Revista Científica Internacional
dc.contributor.uportoCIIMAR - Centro Interdisciplinar de Investigação Marinha e Ambiental
dc.identifier.doi10.1016/j.chroma.2018.07.039
dc.relation.publisherversionhttp://dx.doi.org/10.1016/j.chroma.2018.07.039
Appears in Collections:CIIMAR - Artigo em Revista Científica Internacional

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