Please use this identifier to cite or link to this item: https://hdl.handle.net/10216/120352
Author(s): Cunha I.
Biltes R.
Sales M.G.F.
Vasconcelos V.
Title: Aptamer-based biosensors to detect aquatic phycotoxins and cyanotoxins
Publisher: MDPI
Issue Date: 2018
Abstract: Aptasensors have a great potential for environmental monitoring, particularly for real-time on-site detection of aquatic toxins produced by marine and freshwater microorganisms (cyanobacteria, dinoflagellates, and diatoms), with several advantages over other biosensors that are worth considering. Freshwater monitoring is of vital importance for public health, in numerous human activities, and animal welfare, since these toxins may cause fatal intoxications. Similarly, in marine waters, very effective monitoring programs have been put in place in many countries to detect when toxins exceed established regulatory levels and accordingly enforce shellfish harvesting closures. Recent advances in the fields of aptamer selection, nanomaterials and communication technologies, offer a vast array of possibilities to develop new imaginative strategies to create improved, ultrasensitive, reliable and real-time devices, featuring unique characteristics to produce and amplify the signal. So far, not many strategies have been used to detect aquatic toxins, mostly limited to the optic and electrochemical sensors, the majority applied to detect microcystin-LR using a target-induced switching mode. The limits of detection of these aptasensors have been decreasing from the nM to the fM order of magnitude in the past 20 years. Aspects related to sensor components, performance, aptamers sequences, matrices analyzed and future perspectives, are considered and discussed. © 2018 by the authors. Licensee MDPI, Basel, Switzerland.
Subject: Biosensors
Climate change
Electrochemical sensors
Environmental engineering
Metabolites
Water
Aptasensors
Emerging toxins
Environmental Monitoring
Harmful algal blooms
Water safety
Toxic materials
aptamer
fresh water
marine toxin
sea water
animal
aquatic species
chemistry
cyanobacterium
diatom
dinoflagellate
environmental monitoring
genetic procedures
human
procedures
Animals
Aptamers, Nucleotide
Aquatic Organisms
Biosensing Techniques
Cyanobacteria
Diatoms
Dinoflagellida
Environmental Monitoring
Fresh Water
Humans
Marine Toxins
Seawater
URI: https://hdl.handle.net/10216/120352
Source: Sensors, vol. 18(7):2367
Document Type: Artigo em Revista Científica Internacional
Rights: openAccess
Appears in Collections:CIIMAR - Artigo em Revista Científica Internacional

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