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Author(s): Martins, T
Valentim, AM
Pereira, N
Antunes, LM
Title: Anaesthesia and analgesia in laboratory adult zebrafish: a question of refinement
Publisher: Laboratory Animals
Issue Date: 2016
Abstract: Anaesthesia is used daily in fish experimental procedures; however, the use of an inadequate anaesthetic protocol can compromise not only the animal's welfare but also the reliability of results. The use of zebrafish (Danio rerio) in biomedical research has increased in the last decades, highlighting the importance of appropriate anaesthetic regimens for this species. This article reviews the main anaesthetic agents and protocols used in laboratory adult zebrafish, and some of the analgesic methods to be used in this species that still need more research. In addition, a systematized observation of signs is proposed to evaluate adult zebrafish welfare to reduce pain and distress.
Subject: Analgesia/utilization
Anesthetics/therapeutic use
Animal welfare
Pain Measurement/methods
Research Design
Series: Laboratory animals, vol. 50(6), p. 476-488
Related Information: info:eu-repo/grantAgreement/FCT/5876/147341/PT
Document Type: Artigo em Revista Científica Internacional
Rights: openAccess
Appears in Collections:I3S - Artigo em Revista Científica Internacional

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