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https://hdl.handle.net/10216/115742
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DC Field | Value | Language |
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dc.creator | Anabela Borges | |
dc.creator | Lopez Romero, JC | |
dc.creator | Oliveira, D. | |
dc.creator | Giaouris, E | |
dc.creator | Simões M | |
dc.date.accessioned | 2022-09-15T19:29:56Z | - |
dc.date.available | 2022-09-15T19:29:56Z | - |
dc.date.issued | 2017 | |
dc.identifier.issn | 1364-5072 | |
dc.identifier.other | sigarra:201741 | |
dc.identifier.uri | https://hdl.handle.net/10216/115742 | - |
dc.description.abstract | AimsThe aim of this study was to investigate the antibiofilm potential of five essential oil (EO) components with cyclic (sabineneSAB, carveolC1, carvoneC2) and acyclic (citronellolC3 and citronellalC4) structures against Escherichia coli and Staphylococcus aureus. Methods and ResultsThe selected EO components prevented biofilm set-up, with C3 and C4 causing remarkable effects. When applied against pre-established biofilms, they promoted high biomass removal and inactivation of biofilm cells. Moreover, no viable E.coli biofilm cells were detected after exposure to SAB at 5xMIC and 10xMIC, and a significant viability decrease was observed for both bacteria with the other EO components. SAB, C3 and C4 caused the most prominent effects apparently due to their octanol-water partition coefficient (Po/w), the number of rotatable bonds (n-ROTB) and the free hydroxyl groups. ConclusionsThe overall results demonstrated that the selected EO components, particularly SAB, C3 and C4 are of interest as new lead molecules to both prevent biofilm set-up and to control pre-established biofilms of E.coli and S. aureus. Significance and Impact of the StudyThe tested EO components exhibited prominent antibiofilm properties against E.coli and S. aureus providing a novel and effective alternative/complementary approach to counteract chronic infections and the transmission of diseases in clinical settings. | |
dc.language.iso | eng | |
dc.relation | info:eu-repo/grantAgreement/FCT - Fundação para a Ciência e a Tecnologia/Projetos Estratégicos/UID/EQU/00511/2013 - POCI-01-0145-FEDER-006939/Laboratório de Engenharia de Processos, Ambiente, Biotecnologia e Energia/LEPABE | |
dc.rights | restrictedAccess | |
dc.title | Prevention, removal and inactivation of Escherichia coli and Staphylococcus aureus biofilms using selected monoterpenes of essential oils | |
dc.type | Artigo em Revista Científica Internacional | |
dc.contributor.uporto | Faculdade de Engenharia | |
dc.identifier.doi | 10.1111/jam.13490 | |
dc.identifier.authenticus | P-00M-WSC | |
Appears in Collections: | FEUP - Artigo em Revista Científica Internacional |
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File | Description | Size | Format | |
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201741.pdf Restricted Access | 465.62 kB | Adobe PDF | Request a copy from the Author(s) |
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