Please use this identifier to cite or link to this item:
van Leth, F
|Title:||Beyond multidrug-resistant tuberculosis in Europe: a TBNET study|
|Abstract:||The emergence of drug-resistant tuberculosis (TB) is a challenge to TB control in Europe. We evaluated second-line drug susceptibility testing in Mycobacterium tuberculosis isolates from patients with multidrug-resistant, pre-extensively drug-resistant (pre-XDR-TB) and XDR-TB at 23 TBNET sites in 16 European countries. Over 30% of bacilli from patients with pre-XDR-TB showed resistance to any fluoroquinolone and almost 70% to any second-line injectable drug. Respectively >90% and >80% of the XDR-TB strains tested showed phenotypic resistance to pyrazinamide and ethambutol. Resistance to prothionamide/ethionamide was high in bacilli from pre-XDR-TB patients (43%) and XDR-TB patients (49%).|
|Source:||Int J Tuberc Lung Dis, vol. 19(12), p. 1524-1527|
|Document Type:||Artigo em Revista Científica Internacional|
|Appears in Collections:||ISPUP - Artigo em Revista Científica Internacional|
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.