Utilize este identificador para referenciar este registo:
https://hdl.handle.net/10216/109570Registo completo
| Campo DC | Valor | Idioma |
|---|---|---|
| dc.creator | Pereira, L | |
| dc.creator | Gonçalves, J | |
| dc.creator | Franco-Duarte, R | |
| dc.creator | Silva, J | |
| dc.creator | Rocha, T | |
| dc.creator | Arnold, C | |
| dc.creator | Richards, M | |
| dc.creator | Macaulay, V | |
| dc.date.accessioned | 2017-12-21T17:04:51Z | - |
| dc.date.available | 2017-12-21T17:04:51Z | - |
| dc.date.issued | 2007 | |
| dc.identifier.issn | 0737-4038 | |
| dc.identifier.uri | http://hdl.handle.net/10216/109570 | - |
| dc.description.abstract | The first complete mitochondrial DNA (mtDNA) sequences (approximately 16,569 bp) in 20 patients with asthenozoospermia and a comparison with 23 new complete mtDNA sequences in teratoasthenozoospermic individuals, confirmed no sharing of specific polymorphisms or specific mitochondrial lineages between these individuals. This is strong evidence against the accepted claim of a major role played by mtDNA in male fertility, once supported by haplogroup association studies based on the screening of hypervariable region I. The hypothesis of maternally driven selection acting in male reproductive success must thus be treated with caution. | |
| dc.description.sponsorship | This work was partially supported by Fundação para a Ciência e a Tecnologia—Programa de Financiamento Plirianual do Centro de Investigação de Genética Molecular Humana and by Research Project POCTI/SAU/97/2001 from Fundação para a Ciência e a Tecnologia. | |
| dc.language.iso | eng | |
| dc.publisher | Oxford University Press | |
| dc.relation | info:eu-repo/grantAgreement/FCT/POCI/930/PT | |
| dc.relation.ispartof | Molecular Biology and Evolution, vol. 24(3), p. 868-74 | |
| dc.rights | restrictedAccess | |
| dc.subject | mtDNA | |
| dc.subject | Complete sequences | |
| dc.subject | Asthenozoospermia | |
| dc.subject | Association | |
| dc.title | No evidence for an mtDNA role in sperm motility: data from complete sequencing of asthenozoospermic males | |
| dc.type | Artigo em Revista Científica Internacional | |
| dc.contributor.uporto | Instituto de Investigação e Inovação em Saúde | |
| dc.identifier.doi | 10.1093/molbev/msm004 | |
| dc.relation.publisherversion | https://academic.oup.com/mbe/article/24/3/868/1247055 | |
| Aparece nas coleções: | I3S - Artigo em Revista Científica Internacional | |
Ficheiros deste registo:
| Ficheiro | Descrição | Tamanho | Formato | |
|---|---|---|---|---|
| Pereira2007MBE.pdf Restricted Access | 140.13 kB | Adobe PDF | Ver/Abrir | |
| Pereira2007MBE_Supplementary_Data.zip Restricted Access | 71.12 kB | ZIP | Ver/Abrir |
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