Please use this identifier to cite or link to this item: https://repositorio-aberto.up.pt/handle/10216/109266
Author(s): Goios, A
Pereira, L
Bogue, M
Macaulay, V
Amorim, A
Title: MtDNA phylogeny and evolution of laboratory mouse strains
Publisher: Cold Spring Harbor Laboratory Press
Issue Date: 2007
Abstract: Inbred mouse strains have been maintained for more than 100 years, and they are thought to be a mixture of four different mouse subspecies. Although genealogies have been established, female inbred mouse phylogenies remain unexplored. By a phylogenetic analysis of newly generated complete mitochondrial DNA sequence data in 16 strains, we show here that all common inbred strains descend from the same Mus musculus domesticus female wild ancestor, and suggest that they present a different mitochondrial evolutionary process than their wild relatives with a faster accumulation of replacement substitutions. Our data complement forthcoming results on resequencing of a group of priority strains, and they follow recent efforts of the Mouse Phenome Project to collect and make publicly available information on various strains.
Subject: Animals
Base Sequence
DNA Mitochondrial/genetics
Female
Genetic Variation
Likelihood Functions
Mice
Mice Inbred Strains/genetics
Models
Genetic
Molecular Sequence Data
Phylogeny
Sequence Analysis DNA
URI: http://hdl.handle.net/10216/109266
Source: Genome Research, vol. 17(3), p. 293-8
Related Information: info:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBD%2F16518%2F2004/PT
Document Type: Artigo em Revista Científica Internacional
Rights: openAccess
Appears in Collections:I3S - Artigo em Revista Científica Internacional

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