Please use this identifier to cite or link to this item: http://hdl.handle.net/10216/109253
Author(s): Costa, MD
Pereira, JB
Pala, M
Fernandes, V
Olivieri, A
Achilli, A
Perego, UA
Rychkov, S
Naumova, O
Hatina, J
Woodward, SR
Eng, KK
Macaulay, V
Carr, M
Soares, P
Pereira, L
Richards, MB
Title: A substantial prehistoric European ancestry amongst Ashkenazi maternal lineages
Publisher: Nature Publishing Group
Issue Date: 2013
Abstract: The origins of Ashkenazi Jews remain highly controversial. Like Judaism, mitochondrial DNA is passed along the maternal line. Its variation in the Ashkenazim is highly distinctive, with four major and numerous minor founders. However, due to their rarity in the general population, these founders have been difficult to trace to a source. Here we show that all four major founders, ~40% of Ashkenazi mtDNA variation, have ancestry in prehistoric Europe, rather than the Near East or Caucasus. Furthermore, most of the remaining minor founders share a similar deep European ancestry. Thus the great majority of Ashkenazi maternal lineages were not brought from the Levant, as commonly supposed, nor recruited in the Caucasus, as sometimes suggested, but assimilated within Europe. These results point to a significant role for the conversion of women in the formation of Ashkenazi communities, and provide the foundation for a detailed reconstruction of Ashkenazi genealogical history.
Subject: Bayes Theorem
DNA Mitochondrial/genetics
DNA Mitochondrial/history
Founder Effect
Genealogy and Heraldry
Genome Mitochondrial
Haplotypes
History 15th Century History
Ancient
History Medieval
Humans
Inheritance Patterns
Jews/genetics
Jews/history
Male
Phylogeny
Phylogeography
URI: http://hdl.handle.net/10216/109253
Source: Nature Communications, vol. 4:2543
Related Information: info:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBD%2F48372%2F2008/PT
Document Type: Artigo em Revista Científica Internacional
Rights: openAccess
License: http://creativecommons.org/licenses/by/3.0/
Appears in Collections:I3S - Artigo em Revista Científica Internacional



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