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Author(s): D. M. Correia
C. Ribeiro
G. Botelho
J. Borges
C. Lopes
F. Vaz
S. A. C. Carabineiro
A. V. Machado
S. Lanceros-Méndez
Title: Superhydrophilic poly(L-lactic acid) electrospun membranes for biomedical applications obtained by Argon and Oxygen plasma treatment
Issue Date: 2016
Abstract: Poly(l-lactic acid), PLLA, electrospun membranes and films were plasma treated at different times andpower with argon (Ar) and oxygen (O2), independently, in order to modify the hydrophobic nature ofthe PLLA membranes. Both Ar and O2 plasma treatments promote an increase in fiber average size ofthe electrospun membranes from 830 ± 282 nm to 866 ± 361 and 1179 ± 397 nm, respectively, for themaximum exposure time (970 s) and power (100W). No influence of plasma treatment was detectedin the physical-chemical characteristics of PLLA, such as chemical structure, polymer phase or degreeof crystallinity. On the other hand, an increase in the roughness of the films was obtained both withargon and oxygen plasma treatments. Surface wettability studies revealed a decrease in the contact anglewith increasing plasma treatment time for a given power and with increasing power for a given time inmembranes and films and superhydrophilic electrospun fiber membranes were obtained. Results showedthat the argon and oxygen plasma treatments can be used to tailor hydrophilicity of PLLA membranesfor biomedical applications. MTT assay results indicated that plasma treatments under Ar and O2 do notinfluence the metabolic activity of MC3T3-E1 pre-osteoblast cells.
Related Information: info:eu-repo/grantAgreement/FCT - Fundação para a Ciência e Tecnologia/Projetos Estratégicos/UID/EQU/50020/2013- POCI-01-0145-FEDER-006984/Laboratório de Processos de Separação e Reação - Laboratório de Catálise e Materiais/LSRE-LCM
Document Type: Artigo em Revista Científica Internacional
Rights: restrictedAccess
Appears in Collections:FEUP - Artigo em Revista Científica Internacional

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